Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome

BACKGROUND: Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically ta...

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Detalles Bibliográficos
Autores principales: Tsui, Dana W. Y., Lam, Y. M. Doris, Lee, Wing S., Leung, Tak Y., Lau, Tze K., Lau, Elizabeth T., Tang, Mary H. Y., Akolekar, Ranjit, Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis, Chim, Stephen S. C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994810/
https://www.ncbi.nlm.nih.gov/pubmed/21152411
http://dx.doi.org/10.1371/journal.pone.0015069

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