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Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line
BACKGROUND: Management of peritoneal dissemination is the most critical problem in gastric cancer. This study was performed to investigate the inhibitory effects of valproic acid (VPA) on a highly peritoneal-seeding cell line of human scirrhous gastric cancer, OCUM-2MD3, and to explore the mechanism...
Autores principales: | Yagi, Yasumichi, Fushida, Sachio, Harada, Shinichi, Kinoshita, Jun, Makino, Isamu, Oyama, Katsunobu, Tajima, Hidehiro, Fujita, Hideto, Takamura, Hiroyuki, Ninomiya, Itasu, Fujimura, Takashi, Ohta, Tetsuo, Yashiro, Masakazu, Hirakawa, Kosei |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994814/ https://www.ncbi.nlm.nih.gov/pubmed/21080974 http://dx.doi.org/10.1186/1756-9966-29-149 |
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