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Efficient Double Fragmentation ChIP-seq Provides Nucleotide Resolution Protein-DNA Binding Profiles
Immunoprecipitated crosslinked protein-DNA fragments typically range in size from several hundred to several thousand base pairs, with a significant part of chromatin being much longer than the optimal length for next-generation sequencing (NGS) procedures. Because these larger fragments may be non-...
Autores principales: | Mokry, Michal, Hatzis, Pantelis, de Bruijn, Ewart, Koster, Jan, Versteeg, Rogier, Schuijers, Jurian, van de Wetering, Marc, Guryev, Victor, Clevers, Hans, Cuppen, Edwin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994895/ https://www.ncbi.nlm.nih.gov/pubmed/21152096 http://dx.doi.org/10.1371/journal.pone.0015092 |
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