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Removal of Heterologous Sequences from Plasmodium falciparum Mutants Using FLPe-Recombinase
Genetically-modified mutants are now indispensable Plasmodium gene-function reagents, which are also being pursued as genetically attenuated parasite vaccines. Currently, the generation of transgenic malaria-parasites requires the use of drug-resistance markers. Here we present the development of an...
Autores principales: | van Schaijk, Ben C. L., Vos, Martijn W., Janse, Chris J., Sauerwein, Robert W., Khan, Shahid M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994908/ https://www.ncbi.nlm.nih.gov/pubmed/21152048 http://dx.doi.org/10.1371/journal.pone.0015121 |
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