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How long is too long? Effects of loop size on G-quadruplex stability

We compared here 80 different sequences containing four tracts of three guanines with loops of variable length (between 1 and 15 bases for unmodified sequences, up to 30 for fluorescently labeled oligonucleotides). All sequences were capable of forming stable quadruplexes, with T(m) above physiologi...

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Detalles Bibliográficos
Autores principales:	Guédin, Aurore, Gros, Julien, Alberti, Patrizia, Mergny, Jean-Louis
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995061/ https://www.ncbi.nlm.nih.gov/pubmed/20660477 http://dx.doi.org/10.1093/nar/gkq639

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