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The terminal loop region controls microRNA processing by Drosha and Dicer

microRNAs are widely expressed, ∼22-nt-long regulatory RNAs. They are first transcribed as much longer primary transcripts, which then undergo a series of processing steps to yield the single-stranded, mature microRNAs, although the mechanisms are incompletely understood. Here, we show that the term...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxiao, Zeng, Yan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995066/
https://www.ncbi.nlm.nih.gov/pubmed/20660014
http://dx.doi.org/10.1093/nar/gkq645