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Genomic analysis of codon, sequence and structural conservation with selective biochemical-structure mapping reveals highly conserved and dynamic structures in rotavirus RNAs with potential cis-acting functions

Rotaviruses are a major cause of acute, often fatal, gastroenteritis in infants and young children world-wide. Virions contain an 11 segment double-stranded RNA genome. Little is known about the cis-acting sequences and structural elements of the viral RNAs. Using a database of 1621 full-length sequ...

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Detalles Bibliográficos
Autores principales:	Li, Wilson, Manktelow, Emily, von Kirchbach, Johann C., Gog, Julia R., Desselberger, Ulrich, Lever, Andrew M.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995077/ https://www.ncbi.nlm.nih.gov/pubmed/20671030 http://dx.doi.org/10.1093/nar/gkq663

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