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Hybridization properties of long nucleic acid probes for detection of variable target sequences, and development of a hybridization prediction algorithm

One of the main problems in nucleic acid-based techniques for detection of infectious agents, such as influenza viruses, is that of nucleic acid sequence variation. DNA probes, 70-nt long, some including the nucleotide analog deoxyribose-Inosine (dInosine), were analyzed for hybridization tolerance...

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Detalles Bibliográficos
Autores principales:	Öhrmalm, Christina, Jobs, Magnus, Eriksson, Ronnie, Golbob, Sultan, Elfaitouri, Amal, Benachenhou, Farid, Strømme, Maria, Blomberg, Jonas
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995084/ https://www.ncbi.nlm.nih.gov/pubmed/20864443 http://dx.doi.org/10.1093/nar/gkq777

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