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Unitary Ca(2+) current through recombinant type 3 InsP(3) receptor channels under physiological ionic conditions
The ubiquitous inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) channel, localized primarily in the endoplasmic reticulum (ER) membrane, releases Ca(2+) into the cytoplasm upon binding InsP(3), generating and modulating intracellular Ca(2+) signals that regulate numerous physiological proc...
Autores principales: | Vais, Horia, Foskett, J. Kevin, Daniel Mak, Don-On |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995152/ https://www.ncbi.nlm.nih.gov/pubmed/21078871 http://dx.doi.org/10.1085/jgp.201010513 |
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