The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase

Upon prolonged activation of the spindle assembly checkpoint, cells escape from mitosis through a mechanism called adaptation or mitotic slippage, which is thought to underlie the resistance of cancer cells to antimitotic drugs. We show that, in budding yeast, this mechanism depends on known essenti...

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Detalles Bibliográficos
Autores principales: Rossio, Valentina, Galati, Elena, Ferrari, Matteo, Pellicioli, Achille, Sutani, Takashi, Shirahige, Katsuhiko, Lucchini, Giovanna, Piatti, Simonetta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995168/
https://www.ncbi.nlm.nih.gov/pubmed/21098112
http://dx.doi.org/10.1083/jcb.201007025

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