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Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes

Actin polymerization drives the extension of pseudopods that trap and engulf phagocytic targets. The polymerized actin subsequently dissociates as the phagocytic vacuole seals and detaches from the plasma membrane. We found that phagosomes formed by engagement of integrins that serve as complement r...

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Detalles Bibliográficos
Autores principales: Bohdanowicz, Michal, Cosío, Gabriela, Backer, Jonathan M., Grinstein, Sergio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995177/
https://www.ncbi.nlm.nih.gov/pubmed/21115805
http://dx.doi.org/10.1083/jcb.201004005