Cargando…
Acetylated microtubules are required for fusion of autophagosomes with lysosomes
BACKGROUND: Autophagy is a dynamic process during which isolation membranes package substrates to form autophagosomes that are fused with lysosomes to form autolysosomes for degradation. Although it is agreed that the LC3II-associated mature autophagosomes move along microtubular tracks, it is still...
Autores principales: | Xie, Rui, Nguyen, Susan, McKeehan, Wallace L, Liu, Leyuan |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995476/ https://www.ncbi.nlm.nih.gov/pubmed/21092184 http://dx.doi.org/10.1186/1471-2121-11-89 |
Ejemplares similares
-
Dual Function Microtubule- and Mitochondria-Associated Proteins Mediate Mitotic Cell Death
por: Liu, Leyuan, et al.
Publicado: (2009) -
Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome–autophagosome fusion
por: Mohan, Nitin, et al.
Publicado: (2019) -
Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes
por: Gradzka, Sylwia, et al.
Publicado: (2018) -
BORC coordinates encounter and fusion of lysosomes with autophagosomes
por: Jia, Rui, et al.
Publicado: (2017) -
LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes
por: Hubert, Virginie, et al.
Publicado: (2016)