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The reductase domain in a Type I fatty acid synthase from the apicomplexan Cryptosporidium parvum: Restricted substrate preference towards very long chain fatty acyl thioesters

BACKGROUND: The apicomplexan Cryptosporidium parvum genome possesses a 25-kb intronless open reading frame (ORF) that predicts a multifunctional Type I fatty acid synthase (CpFAS1) with at least 21 enzymatic domains. Although the architecture of CpFAS1 resembles those of bacterial polyketide synthas...

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Detalles Bibliográficos
Autores principales: Zhu, Guan, Shi, Xiangyu, Cai, Xiaomin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995488/
https://www.ncbi.nlm.nih.gov/pubmed/21092192
http://dx.doi.org/10.1186/1471-2091-11-46