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KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data

BACKGROUND: Most approaches used to find recurrent or differential DNA Copy Number Alterations (CNA) in array Comparative Genomic Hybridization (aCGH) data from groups of tumour samples depend on the discretization of the aCGH data to gain, loss or no-change states. This causes loss of valuable biol...

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Detalles Bibliográficos
Autores principales: de Ronde, Jorma J, Klijn, Christiaan, Velds, Arno, Holstege, Henne, Reinders, Marcel JT, Jonkers, Jos, Wessels, Lodewyk FA
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995794/
https://www.ncbi.nlm.nih.gov/pubmed/21070656
http://dx.doi.org/10.1186/1756-0500-3-298