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Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis
Proteases in the skin are essential to epidermal permeability barrier homeostasis. In addition to their direct proteolytic effects, certain proteases signal to cells by activating protease-activated receptors (PARs), the G-protein-coupled receptors. The expression of functional PAR-2 on human skin a...
Autores principales: | Lee, Sang Eun, Jeong, Se Kyoo, Lee, Seung Hun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995962/ https://www.ncbi.nlm.nih.gov/pubmed/20879045 http://dx.doi.org/10.3349/ymj.2010.51.6.808 |
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