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Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis

Proteases in the skin are essential to epidermal permeability barrier homeostasis. In addition to their direct proteolytic effects, certain proteases signal to cells by activating protease-activated receptors (PARs), the G-protein-coupled receptors. The expression of functional PAR-2 on human skin a...

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Detalles Bibliográficos
Autores principales: Lee, Sang Eun, Jeong, Se Kyoo, Lee, Seung Hun
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995962/
https://www.ncbi.nlm.nih.gov/pubmed/20879045
http://dx.doi.org/10.3349/ymj.2010.51.6.808

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