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Evidence for Varied Aetiologies Regulating the Transmission of Prion Disease: Implications for Understanding the Heritable Basis of Prion Incubation Times

BACKGROUND: Transmissible Spongiform Encephalopathies (TSEs) are a group of progressive fatal neurodegenerative disorders, triggered by abnormal folding of the endogenous prion protein molecule. The encoding gene is a major biological factor influencing the length of the asymptomatic period after in...

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Detalles Bibliográficos
Autores principales: Iyegbe, Conrad O., Abiola, Oduola O., Towlson, Chris, Powell, John F., Whatley, Steven A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996284/
https://www.ncbi.nlm.nih.gov/pubmed/21152031
http://dx.doi.org/10.1371/journal.pone.0014186