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Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes
BACKGROUND: In recent years, several lines of evidence have shown an increase in Parkinson's disease prevalence in rural environments where pesticides are heavily used. Although, the underlying mechanism for neuronal degeneration in sporadic PD remains unknown, mitochondrial dysfunction, oxidat...
Autores principales: | BK, Binukumar, Bal, Amanjit, Kandimalla, Ramesh JL, Gill, Kiran Dip |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996378/ https://www.ncbi.nlm.nih.gov/pubmed/21073741 http://dx.doi.org/10.1186/1756-6606-3-35 |
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