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Functional Identification of the Plasmodium Centromere and Generation of a Plasmodium Artificial Chromosome
The artificial chromosome represents a useful tool for gene transfer, both as cloning vectors and in chromosome biology research. To generate a Plasmodium artificial chromosome (PAC), we had to first functionally identify and characterize the parasite's centromere. A putative centromere (pbcen5...
Autores principales: | Iwanaga, Shiroh, Khan, Shahid M., Kaneko, Izumi, Christodoulou, Zoe, Newbold, Chris, Yuda, Masao, Janse, Chris J., Waters, Andrew P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996609/ https://www.ncbi.nlm.nih.gov/pubmed/20227667 http://dx.doi.org/10.1016/j.chom.2010.02.010 |
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