Molecular Modeling Studies of 4,5-Dihydro-1H-pyrazolo[4,3-h] quinazoline Derivatives as Potent CDK2/Cyclin A Inhibitors Using 3D-QSAR and Docking

CDK2/cyclin A has appeared as an attractive drug targets over the years with diverse therapeutic potentials. A computational strategy based on comparative molecular fields analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) followed by molecular docking studies were perfo...

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Detalles Bibliográficos
Autores principales: Ai, Yong, Wang, Shao-Teng, Sun, Ping-Hua, Song, Fa-Jun
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996803/
https://www.ncbi.nlm.nih.gov/pubmed/21152296
http://dx.doi.org/10.3390/ijms11103705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996803/
https://www.ncbi.nlm.nih.gov/pubmed/21152296
http://dx.doi.org/10.3390/ijms11103705

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