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ChIP on Chip: surprising results are often artifacts
BACKGROUND: The method of chromatin immunoprecipitation combined with microarrays (ChIP-Chip) is a powerful tool for genome-wide analysis of protein binding. However, a high background signal is a common phenomenon. RESULTS: Reinvestigation of the chromatin immunoprecipitation procedure led us to di...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996942/ https://www.ncbi.nlm.nih.gov/pubmed/20602746 http://dx.doi.org/10.1186/1471-2164-11-414 |