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DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions

BACKGROUND: Mitochondria are semi-autonomous, semi-self-replicating organelles harboring their own DNA (mitochondrial DNA, mtDNA), and their dysregulation is involved in the development of various diseases. While mtDNA does not generally undergo epigenetic modifications, almost all mitochondrial pro...

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Detalles Bibliográficos
Autores principales:	Takasugi, Masaki, Yagi, Shintaro, Hirabayashi, Keiji, Shiota, Kunio
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996977/ https://www.ncbi.nlm.nih.gov/pubmed/20723256 http://dx.doi.org/10.1186/1471-2164-11-481

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