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Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated
BACKGROUND: DNA methylation can regulate gene expression by modulating the interaction between DNA and proteins or protein complexes. Conserved consensus motifs exist across the human genome ("predicted transcription factor binding sites": "predicted TFBS") but the large majority...
Autores principales: | Choy, Mun-Kit, Movassagh, Mehregan, Goh, Hock-Guan, Bennett, Martin R, Down, Thomas A, Foo, Roger SY |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997012/ https://www.ncbi.nlm.nih.gov/pubmed/20875111 http://dx.doi.org/10.1186/1471-2164-11-519 |
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