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Efficient Gene Targeting by Homologous Recombination in Rat Embryonic Stem Cells
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombination. To establish whether rat ES cells are amenab...
Autores principales: | Meek, Stephen, Buehr, Mia, Sutherland, Linda, Thomson, Alison, Mullins, John J., Smith, Andrew J., Burdon, Tom |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997056/ https://www.ncbi.nlm.nih.gov/pubmed/21151976 http://dx.doi.org/10.1371/journal.pone.0014225 |
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