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Efficient Gene Targeting by Homologous Recombination in Rat Embryonic Stem Cells

The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombination. To establish whether rat ES cells are amenab...

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Detalles Bibliográficos
Autores principales: Meek, Stephen, Buehr, Mia, Sutherland, Linda, Thomson, Alison, Mullins, John J., Smith, Andrew J., Burdon, Tom
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997056/
https://www.ncbi.nlm.nih.gov/pubmed/21151976
http://dx.doi.org/10.1371/journal.pone.0014225

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