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Correlated conformational events in EF-G and the ribosome regulate translocation

In bacteria, the translocation of tRNA and mRNA with respect to the ribosome is catalyzed by the conserved GTPase, elongation factor-G (EF-G). In order to probe the rate determining features in this process, EF-G-catalyzed translocation was imaged from two unique structural perspectives using single...

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Detalles Bibliográficos
Autores principales: Munro, James B., Wasserman, Michael R., Altman, Roger B., Wang, Leyi, Blanchard, Scott C.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997181/
https://www.ncbi.nlm.nih.gov/pubmed/21057527
http://dx.doi.org/10.1038/nsmb.1925