Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies

HIV-1 envelope glycoprotein gp41 undergoes large conformational changes to drive fusion of viral and target cell membranes, thereby exhibiting at least three distinct conformations during the viral entry process. Neutralizing antibodies against gp41 block HIV-1 infection by targeting its membrane pr...

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Detalles Bibliográficos
Autores principales: Frey, Gary, Chen, Jia, Rits-Volloch, Sophia, Freeman, Michael M., Zolla-Pazner, Susan, Chen, Bing
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997185/
https://www.ncbi.nlm.nih.gov/pubmed/21076402
http://dx.doi.org/10.1038/nsmb.1950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997185/
https://www.ncbi.nlm.nih.gov/pubmed/21076402
http://dx.doi.org/10.1038/nsmb.1950

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