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S. aureus MscL Is a Pentamer In Vivo but of Variable Stoichiometries In Vitro: Implications for Detergent-Solubilized Membrane Proteins

While the bacterial mechanosensitive channel of large conductance (MscL) is the best studied biological mechanosensor and serves as a paradigm for how a protein can sense and respond to membrane tension, the simple matter of its oligomeric state has led to debate, with models ranging from tetramers...

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Detalles Bibliográficos
Autores principales: Dorwart, Michael R., Wray, Robin, Brautigam, Chad A., Jiang, Youxing, Blount, Paul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998437/
https://www.ncbi.nlm.nih.gov/pubmed/21151884
http://dx.doi.org/10.1371/journal.pbio.1000555