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S. aureus MscL Is a Pentamer In Vivo but of Variable Stoichiometries In Vitro: Implications for Detergent-Solubilized Membrane Proteins
While the bacterial mechanosensitive channel of large conductance (MscL) is the best studied biological mechanosensor and serves as a paradigm for how a protein can sense and respond to membrane tension, the simple matter of its oligomeric state has led to debate, with models ranging from tetramers...
Autores principales: | Dorwart, Michael R., Wray, Robin, Brautigam, Chad A., Jiang, Youxing, Blount, Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998437/ https://www.ncbi.nlm.nih.gov/pubmed/21151884 http://dx.doi.org/10.1371/journal.pbio.1000555 |
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