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A sequence-dependent exonuclease activity from Tetrahymena thermophila

BACKGROUND: Telomere function requires a highly conserved G rich 3'- overhang. This structure is formed by 5'-resection of the C-rich telomere strand. However, while many nucleases have been suggested to play a role in processing, it is not yet clear which nucleases carry out this 5'-...

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Detalles Bibliográficos
Autores principales: Tom, Hui-I Kao, Greider, Carol W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998447/
https://www.ncbi.nlm.nih.gov/pubmed/21080963
http://dx.doi.org/10.1186/1471-2091-11-45

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