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Prediction of conformational changes by single mutation in the hepatitis B virus surface antigen (HBsAg) identified in HBsAg-negative blood donors

BACKGROUND: Selection of hepatitis B virus (HBV) by host immunity has been suggested to give rise to variants with amino acid substitutions at or around the 'a' determinant of the surface antigen (HBsAg), the main target of antibody neutralization and diagnostic assays. However, there have...

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Detalles Bibliográficos
Autores principales:	Ie, Susan I, Thedja, Meta D, Roni, Martono, Muljono, David H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998485/ https://www.ncbi.nlm.nih.gov/pubmed/21087462 http://dx.doi.org/10.1186/1743-422X-7-326

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