In vitro gene regulatory networks predict in vivo function of liver

BACKGROUND: Evolution of toxicity testing is predicated upon using in vitro cell based systems to rapidly screen and predict how a chemical might cause toxicity to an organ in vivo. However, the degree to which we can extend in vitro results to in vivo activity and possible mechanisms of action rema...

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Detalles Bibliográficos
Autores principales: Deng, Youping, Johnson, David R, Guan, Xin, Ang, Choo Y, Ai, Junmei, Perkins, Edward J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998496/
https://www.ncbi.nlm.nih.gov/pubmed/21073692
http://dx.doi.org/10.1186/1752-0509-4-153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998496/
https://www.ncbi.nlm.nih.gov/pubmed/21073692
http://dx.doi.org/10.1186/1752-0509-4-153

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