Cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection

We report the systemic cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection. In patients with pneumonia, the serum levels of IFN-γ and IL-5 were significantly higher than those in patients without pneumonia. This tendency was also present for IL-6, IL...

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Detalles Bibliográficos
Autores principales: Takano, T., Tajiri, H., Kashiwagi, Y., Kimura, S., Kawashima, H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998638/
https://www.ncbi.nlm.nih.gov/pubmed/20820834
http://dx.doi.org/10.1007/s10096-010-1041-9
Descripción
Sumario:We report the systemic cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection. In patients with pneumonia, the serum levels of IFN-γ and IL-5 were significantly higher than those in patients without pneumonia. This tendency was also present for IL-6, IL-8, IL-10, IL-13, and MCP-1 in patients with pneumonia. Among patients with pneumonia, the levels of MCP-1 were significantly higher in the group of patients with pneumonia with severe respiratory failure than patients with mild pneumonia.

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