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Concordance of metabolic enzyme genotypes assayed from paraffin-embedded, formalin-fixed breast tumors and normal lymphatic tissue

OBJECTIVES: Translational epidemiology studies often use archived tumor specimens to evaluate genetic hypotheses involving cancer outcomes. When the exposure of interest is a germline polymorphism, a key concern is whether the genotype assayed from tumor-derived DNA is representative of the germline...

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Detalles Bibliográficos
Autores principales: Ahern, Thomas P, Christensen, Mariann, Cronin-Fenton, Deirdre P, Lunetta, Kathryn L, Rosenberg, Carol L, Sørensen, Henrik Toft, Lash, Timothy L, Hamilton-Dutoit, Stephen
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998813/
https://www.ncbi.nlm.nih.gov/pubmed/21152250
http://dx.doi.org/10.2147/CLEP.S13811