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Concordance of metabolic enzyme genotypes assayed from paraffin-embedded, formalin-fixed breast tumors and normal lymphatic tissue
OBJECTIVES: Translational epidemiology studies often use archived tumor specimens to evaluate genetic hypotheses involving cancer outcomes. When the exposure of interest is a germline polymorphism, a key concern is whether the genotype assayed from tumor-derived DNA is representative of the germline...
Autores principales: | Ahern, Thomas P, Christensen, Mariann, Cronin-Fenton, Deirdre P, Lunetta, Kathryn L, Rosenberg, Carol L, Sørensen, Henrik Toft, Lash, Timothy L, Hamilton-Dutoit, Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998813/ https://www.ncbi.nlm.nih.gov/pubmed/21152250 http://dx.doi.org/10.2147/CLEP.S13811 |
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