Developments in low-resolution biological X-ray crystallography

Despite the recent substantial technological developments in X-ray crystallography, solving and refining structures at low resolutions remain substantial challenges. Many macromolecular crystals, especially those of large molecules or multicomponent assemblies, diffract X-rays to resolutions that ar...

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Detalles Bibliográficos
Autor principal: Dyda, Fred
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998839/
https://www.ncbi.nlm.nih.gov/pubmed/21170372
http://dx.doi.org/10.3410/B2-80
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author Dyda, Fred
author_facet Dyda, Fred
author_sort Dyda, Fred
collection PubMed
description Despite the recent substantial technological developments in X-ray crystallography, solving and refining structures at low resolutions remain substantial challenges. Many macromolecular crystals, especially those of large molecules or multicomponent assemblies, diffract X-rays to resolutions that are worse than 3.5Å. This report summarizes several recent advances aiding low resolution crystallographic work.
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spelling pubmed-29988392010-12-17 Developments in low-resolution biological X-ray crystallography Dyda, Fred F1000 Biol Rep Review Article Despite the recent substantial technological developments in X-ray crystallography, solving and refining structures at low resolutions remain substantial challenges. Many macromolecular crystals, especially those of large molecules or multicomponent assemblies, diffract X-rays to resolutions that are worse than 3.5Å. This report summarizes several recent advances aiding low resolution crystallographic work. Faculty of 1000 Ltd 2010-11-11 /pmc/articles/PMC2998839/ /pubmed/21170372 http://dx.doi.org/10.3410/B2-80 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Dyda, Fred
Developments in low-resolution biological X-ray crystallography
title Developments in low-resolution biological X-ray crystallography
title_full Developments in low-resolution biological X-ray crystallography
title_fullStr Developments in low-resolution biological X-ray crystallography
title_full_unstemmed Developments in low-resolution biological X-ray crystallography
title_short Developments in low-resolution biological X-ray crystallography
title_sort developments in low-resolution biological x-ray crystallography
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998839/
https://www.ncbi.nlm.nih.gov/pubmed/21170372
http://dx.doi.org/10.3410/B2-80
work_keys_str_mv AT dydafred developmentsinlowresolutionbiologicalxraycrystallography

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