Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice

OBJECTIVE: Functional studies show that disruption of endothelial surface layer (ESL) is accompanied by enhanced sensitivity of the vasculature towards atherogenic stimuli. However, relevance of ESL disruption as causal mechanism for vascular dysfunction remains to be demonstrated. We examined if lo...

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Detalles Bibliográficos
Autores principales: Meuwese, Marijn C., Broekhuizen, Lysette N., Kuikhoven, Mayella, Heeneman, Sylvia, Lutgens, Esther, Gijbels, Marion J. J., Nieuwdorp, Max, Peutz, Carine J., Stroes, Erik S. G., Vink, Hans, van den Berg, Bernard M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999536/
https://www.ncbi.nlm.nih.gov/pubmed/21170388
http://dx.doi.org/10.1371/journal.pone.0014262

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