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Relationships Linking Amplification Level to Gene Over-Expression in Gliomas
BACKGROUND: Gene amplification is thought to promote over-expression of genes favouring tumour development. Because amplified regions are usually megabase-long, amplification often concerns numerous syntenic or non-syntenic genes, among which only a subset is over-expressed. The rationale for these...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999539/ https://www.ncbi.nlm.nih.gov/pubmed/21170331 http://dx.doi.org/10.1371/journal.pone.0014249 |