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A Differential Drug Screen for Compounds That Select Against Antibiotic Resistance
Antibiotics increase the frequency of resistant bacteria by providing them a competitive advantage over sensitive strains. Here, we develop a versatile assay for differential chemical inhibition of competing microbial strains, and use it to identify compounds that preferentially inhibit tetracycline...
Autores principales: | Chait, Remy, Shrestha, Shreya, Shah, Aakash Kaushik, Michel, Jean-Baptiste, Kishony, Roy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999542/ https://www.ncbi.nlm.nih.gov/pubmed/21209699 http://dx.doi.org/10.1371/journal.pone.0015179 |
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