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Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification
BACKGROUND: It is quite important to simulate the metabolic changes of a cell in response to the change in culture environment and/or specific gene knockouts particularly for the purpose of application in industry. If this could be done, the cell design can be made without conducting exhaustive expe...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999585/ https://www.ncbi.nlm.nih.gov/pubmed/21092096 http://dx.doi.org/10.1186/1475-2859-9-88 |