Small cell carcinoma in ulcerative colitis - new treatment option: a case report

BACKGROUND: The most common type of carcinoma associated with ulcerative colitis (UC) is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC. METHODS: A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual fol...

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Detalles Bibliográficos
Autores principales: Kosmidis, Christoforos, Efthimiadis, Christoforos, Anthimidis, Georgios, Vasiliadou, Kalliopi, Tzeveleki, Ioanna, Fotiadis, Panagiotis, Basdanis, Georgios
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999595/
https://www.ncbi.nlm.nih.gov/pubmed/21087512
http://dx.doi.org/10.1186/1477-7819-8-100
Descripción
Sumario:BACKGROUND: The most common type of carcinoma associated with ulcerative colitis (UC) is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC. METHODS: A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual follow-up and presented with mucoid-bloody diarrhea. Colonoscopy revealed a rectal mass 2 cm distant from the anal verge. The patient underwent a total proctocolectomy with preservation of the anal sphincters, construction of an ileal reservoir, anastomosis of the reservoir to the anus (J configuration) and protective loop ileostomy. RESULTS: Histological examination showed undifferentiated small cell carcinoma. CONCLUSIONS: This is the first case of small cell carcinoma in a background of UC reported to be treated surgically and the patient and has no reccurence 18 months postoperatively.

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