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The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities

BACKGROUND: Marek's disease virus (MDV) is an oncogenic herpesvirus, which causes malignant lymphoma in chickens. The Meq protein of MDV, which is expressed abundantly in MDV-infected cells and in Marek's disease (MD) tumor cells, functions as a transcriptional activator and has been propo...

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Detalles Bibliográficos
Autores principales: Deng, Xufang, Li, Xiangdong, Shen, Yang, Qiu, Yafeng, Shi, Zixue, Shao, Donghua, Jin, Yamei, Chen, Hongjun, Ding, Chan, Li, Li, Chen, Puyan, Ma, Zhiyong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999606/
https://www.ncbi.nlm.nih.gov/pubmed/21110861
http://dx.doi.org/10.1186/1743-422X-7-348