Cargando…

The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities

BACKGROUND: Marek's disease virus (MDV) is an oncogenic herpesvirus, which causes malignant lymphoma in chickens. The Meq protein of MDV, which is expressed abundantly in MDV-infected cells and in Marek's disease (MD) tumor cells, functions as a transcriptional activator and has been propo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Xufang, Li, Xiangdong, Shen, Yang, Qiu, Yafeng, Shi, Zixue, Shao, Donghua, Jin, Yamei, Chen, Hongjun, Ding, Chan, Li, Li, Chen, Puyan, Ma, Zhiyong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999606/ https://www.ncbi.nlm.nih.gov/pubmed/21110861 http://dx.doi.org/10.1186/1743-422X-7-348

Ejemplares similares

Marek’s disease virus oncoprotein Meq physically interacts with the chicken infectious anemia virus-encoded apoptotic protein apoptin
por: Brown, Andrew C., et al.
Publicado: (2018)

Marek’s disease virus Meq oncoprotein interacts with chicken HDAC 1 and 2 and mediates their degradation via proteasome dependent pathway
por: Liao, Yifei, et al.
Publicado: (2021)

Transcriptional Profiling of MEq-Dependent Genes in Marek’s Disease Resistant and Susceptible Inbred Chicken Lines
por: Subramaniam, Sugalesini, et al.
Publicado: (2013)

Research Note: Characterization of S-Meq containing the deletion in Meq protein's transactivation domain in a Marek's disease virus strain in Japan
por: Murata, Shiro, et al.
Publicado: (2021)

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus
por: Sun, Peng, et al.
Publicado: (2020)

Positive Selection Drives Rapid Evolution of the meq Oncogene of Marek’s Disease Virus
por: Padhi, Abinash, et al.
Publicado: (2016)

Sequence analysis of Meq oncogene among Indian isolates of Marek's disease herpesvirus
por: Gupta, Mridula, et al.
Publicado: (2016)

Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek’s Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses
por: Teng, Man, et al.
Publicado: (2023)

Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek's disease virus
por: Li, Yanpeng, et al.
Publicado: (2011)

Diversity of Meq gene from clinical Marek’s disease virus infection in Saudi Arabia
por: Mohamed, Mahmoud H. A., et al.
Publicado: (2016)

Newly detected mutations in the Meq oncogene and molecular pathotyping of very virulent Marek’s disease herpesvirus in Tunisia
por: Lachheb, Jihene, et al.
Publicado: (2020)

Transcriptional analysis of immune-related gene expression in p53-deficient mice with increased susceptibility to influenza A virus infection
por: Yan, Wenjun, et al.
Publicado: (2015)

A Review on the Marek’s Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021
por: Song, Baolin, et al.
Publicado: (2022)

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence
por: Sato, Jumpei, et al.
Publicado: (2022)

Characterization of nonstructural protein 3 of a neurovirulent Japanese encephalitis virus strain isolated from a pig
por: Deng, Xufang, et al.
Publicado: (2011)

Deletion of the Viral Thymidine Kinase in a Meq-Deleted Recombinant Marek’s Disease Virus Reduces Lymphoid Atrophy but Is Less Protective
por: Conrad, Steven J., et al.
Publicado: (2021)

Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse model
por: Shi, Zixue, et al.
Publicado: (2014)

Marek’s Disease Virus Activates the PI3K/Akt Pathway Through Interaction of Its Protein Meq With the P85 Subunit of PI3K to Promote Viral Replication
por: Li, Huimin, et al.
Publicado: (2018)

Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection
por: Sun, Aijun, et al.
Publicado: (2022)

Tumor suppressor p53 protects mice against Listeria monocytogenes infection
por: Wang, Shaohui, et al.
Publicado: (2016)

p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication
por: Wang, Xin, et al.
Publicado: (2020)

Chuwi meq'en ja' = Comunidad y liderazgo en la Guatemala K'iche'
por: Ekern, Stener
Publicado: (2010)

Nonstructural Protein 1 of Influenza A Virus Interacts with Human Guanylate-Binding Protein 1 to Antagonize Antiviral Activity
por: Zhu, Zixiang, et al.
Publicado: (2013)

Data on meq gene sequence analysis of Ludhiana MDV isolates
por: Gupta, Mridula, et al.
Publicado: (2016)

The prognostic validity of the formative for the summative MEQ (Modified Essay Questions)
por: Büssing, Oliver, et al.
Publicado: (2021)

Transcripts of antibacterial peptides in chicken erythrocytes infected with Marek’s disease virus
por: Niu, Sheng, et al.
Publicado: (2018)

Detection of p53 mutation and serum monitoring alert caused by Marek’s disease virus in poultry
por: Zhang, Huixia, et al.
Publicado: (2020)

Proposal for the award of a contract for civil-engineering work for the construction of the MEQ59 platform
Publicado: (2017)

Successful treatment in the patient with serum sodium level greater than 200 mEq/L.
por: Park, Y. J., et al.
Publicado: (2000)

Cardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report
por: Amiri, Hassan, et al.
Publicado: (2016)

Reliability and Validity of the Malay Mindful Eating Questionnaire (MEQ-M) among Overweight and Obese Adults
por: Abdul Basir, Siti Munirah, et al.
Publicado: (2021)

Deletion of 1.8-kb mRNA of Marek's disease virus decreases its replication ability but not oncogenicity
por: Sun, Aijun, et al.
Publicado: (2010)

Structural insights into the transcription-independent apoptotic pathway of p53
por: Chi, Seung-Wook
Publicado: (2014)

The Viral Oncoprotein LMP1 Exploits TRADD for Signaling by Masking Its Apoptotic Activity
por: Schneider, Frank, et al.
Publicado: (2008)

Co-Infection with Marek’s Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek’s Disease Vaccine Efficacy
por: Sun, Guo-Rong, et al.
Publicado: (2017)

Recombinant Marek’s disease virus type 1 provides full protection against very virulent Marek’s and infectious bursal disease viruses in chickens
por: Li, Kai, et al.
Publicado: (2016)

Molecular Characterization of Enterohemorrhagic E. coli O157 Isolated from Animal Fecal and Food Samples in Eastern China
por: Wang, Shaohui, et al.
Publicado: (2014)

The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus
por: Warren, Wesley C., et al.
Publicado: (2023)

Sodium zirconium cyclosilicate (ZS-9) treatment in patients with serum potassium >6.5 mEq/L
por: Rasmussen, Henrik
Publicado: (2015)

Targeting the Pulmonary Microbiota to Fight against Respiratory Diseases
por: Li, Zongjie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8k7g463hnh5adk6ks8ug1pq6s2