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Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in Plasmodium vivax field isolates that failed chloroquine treatment

BACKGROUND: To use pyrimethamine as an alternative anti-malarial drug for chloroquine-resistant malaria parasites, it was necessary to determine the enzyme's genetic variation in dihydrofolate reductase-thymidylate syntase (DHFR-TS) among Korean strains. METHODS: Genetic variation of dhfr-ts ge...

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Detalles Bibliográficos
Autores principales:	Lee, Won-Ja, Kim, Hyung-Hwan, Choi, Yien-Kyoung, Choi, Kyung-Mi, Kim, Mi-A, Kim, Jung-Yeon, Sattabongkot, Jetsumon, Sohn, Youngjoo, Kim, Hyuck, Lee, Jong-Koo, Park, Han-Sook, Lee, Hyeong-Woo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999615/ https://www.ncbi.nlm.nih.gov/pubmed/21087471 http://dx.doi.org/10.1186/1475-2875-9-331

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