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The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats
OBJECTIVE: The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats. METHODS: First, amitriptyline was administered intraperitoneally (i.p.) at doses of 20, 40 and 80 mg kg(-1), 30 min before sub...
Autores principales: | Hajhashemi, Valiollah, Sadeghi, Hossein, Minaiyan, Mohsen, Movahedian, Ahmad, Talebi, Ardeshir |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999717/ https://www.ncbi.nlm.nih.gov/pubmed/21243294 http://dx.doi.org/10.1590/S1807-59322010001100022 |
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