Calcium and Neurogenesis in Alzheimer's Disease

It was evidenced that impairment of calcium homeostasis is a potential mechanism in the development of Alzheimer's disease (AD). It remains, however, unclear how the calcium signaling are associated with in AD progression. Here we review recent studies to discuss the relationship among the sign...

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Detalles Bibliográficos
Autores principales: Wang, Jun Ming, Sun, Chenyou
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999846/
https://www.ncbi.nlm.nih.gov/pubmed/21151820
http://dx.doi.org/10.3389/fnins.2010.00194
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author Wang, Jun Ming
Sun, Chenyou
author_facet Wang, Jun Ming
Sun, Chenyou
author_sort Wang, Jun Ming
collection PubMed
description It was evidenced that impairment of calcium homeostasis is a potential mechanism in the development of Alzheimer's disease (AD). It remains, however, unclear how the calcium signaling are associated with in AD progression. Here we review recent studies to discuss the relationship among the signaling of intracellular calcium concentration, neurogenic activity, and AD progression. Analyzing these findings may provide new ideas to improve the neurogenic status in pathological processes in the aging brain.
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spelling pubmed-29998462010-12-10 Calcium and Neurogenesis in Alzheimer's Disease Wang, Jun Ming Sun, Chenyou Front Neurosci Neuroscience It was evidenced that impairment of calcium homeostasis is a potential mechanism in the development of Alzheimer's disease (AD). It remains, however, unclear how the calcium signaling are associated with in AD progression. Here we review recent studies to discuss the relationship among the signaling of intracellular calcium concentration, neurogenic activity, and AD progression. Analyzing these findings may provide new ideas to improve the neurogenic status in pathological processes in the aging brain. Frontiers Research Foundation 2010-12-02 /pmc/articles/PMC2999846/ /pubmed/21151820 http://dx.doi.org/10.3389/fnins.2010.00194 Text en Copyright © 2010 Wang and Sun. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
spellingShingle Neuroscience
Wang, Jun Ming
Sun, Chenyou
Calcium and Neurogenesis in Alzheimer's Disease
title Calcium and Neurogenesis in Alzheimer's Disease
title_full Calcium and Neurogenesis in Alzheimer's Disease
title_fullStr Calcium and Neurogenesis in Alzheimer's Disease
title_full_unstemmed Calcium and Neurogenesis in Alzheimer's Disease
title_short Calcium and Neurogenesis in Alzheimer's Disease
title_sort calcium and neurogenesis in alzheimer's disease
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999846/
https://www.ncbi.nlm.nih.gov/pubmed/21151820
http://dx.doi.org/10.3389/fnins.2010.00194
work_keys_str_mv AT wangjunming calciumandneurogenesisinalzheimersdisease
AT sunchenyou calciumandneurogenesisinalzheimersdisease

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