Cargando…

Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase

Stearoyl-CoA desaturase-1 (SCD1) is a key enzyme in fatty acid and energy metabolism, but little is known about its nutritional regulation. Dietary methionine restriction in rats decreases hepatic Scd1 mRNA and protein, increases energy expenditure, and decreases fat-pad mass/body-weight% (FM/BW%)....

Descripción completa

Detalles Bibliográficos
Autores principales:	Elshorbagy, Amany K., Valdivia-Garcia, Maria, Mattocks, Dwight A. L., Plummer, Jason D., Smith, A. David, Drevon, Christian A., Refsum, Helga, Perrone, Carmen E.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999932/ https://www.ncbi.nlm.nih.gov/pubmed/20871132 http://dx.doi.org/10.1194/jlr.M010215

Ejemplares similares

The Association of Cysteine with Obesity, Inflammatory Cytokines and Insulin Resistance in Hispanic Children and Adolescents
por: Elshorbagy, Amany K., et al.
Publicado: (2012)

Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study
por: Olsen, Thomas, et al.
Publicado: (2020)

Inhibition of stearoyl-coenzyme A desaturase 1 ameliorates hepatic steatosis by inducing AMPK-mediated lipophagy
por: Zhou, Youping, et al.
Publicado: (2020)

A Stearoyl–Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α‐Synuclein Mice
por: Nuber, Silke, et al.
Publicado: (2020)

Susceptibility of Pancreatic Beta Cells to Fatty Acids Is Regulated by LXR/PPARα-Dependent Stearoyl-Coenzyme A Desaturase
por: Hellemans, Karine H., et al.
Publicado: (2009)

Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells
por: Zhang, Jun, et al.
Publicado: (2013)

Sodium Orthovanadate Changes Fatty Acid Composition and Increased Expression of Stearoyl-Coenzyme A Desaturase in THP-1 Macrophages
por: Korbecki, Jan, et al.
Publicado: (2019)

Cysteine restriction‐specific effects of sulfur amino acid restriction on lipid metabolism
por: Nichenametla, Sailendra N., et al.
Publicado: (2022)

Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis
por: Tian, Huibin, et al.
Publicado: (2022)

Global deficiency of stearoyl-CoA desaturase-2 protects against diet-induced adiposity
por: O’Neill, Lucas M., et al.
Publicado: (2020)

Dietary cystine level affects metabolic rate and glycaemic control in adult mice()()
por: Elshorbagy, Amany K., et al.
Publicado: (2012)

A Phase 1 Randomized, Placebo‐Controlled Trial With a Topical Inhibitor of Stearoyl‐Coenzyme A Desaturase 1 Under Occluded and Nonoccluded Conditions
por: Brigandi, Richard A., et al.
Publicado: (2019)

The Evolutionary Pattern and the Regulation of Stearoyl-CoA Desaturase Genes
por: Wu, Xiaoyun, et al.
Publicado: (2013)

Stearoyl-CoA Desaturase Is Essential for Porcine Adipocyte Differentiation
por: Liu, Lulu, et al.
Publicado: (2020)

Role of Stearoyl-CoA Desaturase 1 in Cardiovascular Physiology
por: Balatskyi, Volodymyr V., et al.
Publicado: (2023)

Discovery of Tumor-Specific Irreversible Inhibitors of Stearoyl CoA Desaturase
por: Theodoropoulos, Panayotis C., et al.
Publicado: (2016)

Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans
por: Elshorbagy, A K, et al.
Publicado: (2016)

The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates
por: Castro, L Filipe C, et al.
Publicado: (2011)

Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease
por: Astarita, Giuseppe, et al.
Publicado: (2011)

X-ray Structure of a Mammalian Stearoyl-CoA Desaturase
por: Bai, Yonghong, et al.
Publicado: (2015)

Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease
por: O’Neill, Lucas M., et al.
Publicado: (2020)

Fatty acid profiles and Delta9 desaturase (stearoyl-CoA desaturase; SCD 1) expression in adipose tissue surrounding benign and malignant breast tumors
por: Sefidabi, Reyhaneh, et al.
Publicado: (2023)

The Association of Circulating Amino Acids and Dietary Inflammatory Potential with Muscle Health in Chinese Community-Dwelling Older People
por: Su, Yi, et al.
Publicado: (2022)

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer
por: Oatman, Nicole, et al.
Publicado: (2021)

Effects of short-term methionine and cysteine restriction and enrichment with polyunsaturated fatty acids on oral glucose tolerance, plasma amino acids, fatty acids, lactate and pyruvate: results from a pilot study
por: Olsen, Thomas, et al.
Publicado: (2021)

Regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase
por: Shi, Xun, et al.
Publicado: (2013)

Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression
por: Li, Weihua, et al.
Publicado: (2018)

Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer
por: Tracz-Gaszewska, Zuzanna, et al.
Publicado: (2019)

Stearoyl-CoA Desaturase Regulates Angiogenesis and Energy Metabolism in Ischemic Cardiomyocytes
por: Gan, Ana-Maria, et al.
Publicado: (2022)

Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages
por: Lin, Joseph B., et al.
Publicado: (2023)

Increased expression of the gene encoding stearoyl-CoA desaturase 1 in human bladder cancer
por: Presler, M., et al.
Publicado: (2018)

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
por: Bogie, Jeroen F.J., et al.
Publicado: (2020)

Effects of overfeeding on the fatty acid profile and stearoyl-CoA desaturase-1 indices in the liver and subcutaneous adipose tissue in cats
por: IWAZAKI, Eiji, et al.
Publicado: (2019)

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells
por: Noto, A, et al.
Publicado: (2013)

Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
por: Zhou, Xian, et al.
Publicado: (2021)

Postprandial effects of a meal low in sulfur amino acids and high in polyunsaturated fatty acids compared to a meal high in sulfur amino acids and saturated fatty acids on stearoyl CoA-desaturase indices and plasma sulfur amino acids: a pilot study
por: Olsen, Thomas, et al.
Publicado: (2020)

Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions
por: Breuer, Sebastian, et al.
Publicado: (2004)

Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells
por: Wang, Lingling, et al.
Publicado: (2022)

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1
por: Shen, Jiemin, et al.
Publicado: (2023)

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1
por: Shen, Jiemin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5pq778qbihs0dchii3ntsd2ud6