Cargando…
Neuroprotective Properties of Mildronate, a Small Molecule, in a Rat Model of Parkinson’s Disease
Previously, we have found that mildronate [3-(2,2,2-trimethylhydrazinium) propionate dihydrate], a small molecule with charged nitrogen and oxygen atoms, protects mitochondrial metabolism that is altered by inhibitors of complex I and has neuroprotective effects in an azidothymidine-neurotoxicity mo...
Autores principales: | Klusa, Vija Z., Isajevs, Sergejs, Svirina, Darja, Pupure, Jolanta, Beitnere, Ulrika, Rumaks, Juris, Svirskis, Simons, Jansone, Baiba, Dzirkale, Zane, Muceniece, Ruta, Kalvinsh, Ivars, Vinters, Harry V. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000094/ https://www.ncbi.nlm.nih.gov/pubmed/21151450 http://dx.doi.org/10.3390/ijms11114465 |
Ejemplares similares
-
GABAA agonist muscimol ameliorates learning/memory deficits in streptozocin-induced Alzheimer’s disease non-transgenic rat model
por: Pilipenko, Vladimirs, et al.
Publicado: (2015) -
Intra-Nasally Administered Oligopeptide Lunasin Acts as a Possible Anti-Psychotic Agent in Mice Models
por: Dzirkale, Zane, et al.
Publicado: (2019) -
Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improves Motor Symptoms and Normalizes Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6‐Hydroxydopamine‐Treated Rats
por: Narbute, Karīna, et al.
Publicado: (2019) -
A Novel 1,4-Dihydropyridine Derivative Improves Spatial Learning and Memory and Modifies Brain Protein Expression in Wild Type and Transgenic APP(SweDI) Mice
por: Jansone, Baiba, et al.
Publicado: (2015) -
Characterization of the transporterB(0)AT3 (Slc6a17) in the rodent central nervous system
por: Hägglund, Maria GA, et al.
Publicado: (2013)