Fluoroquinolone Use and Clostridium difficile–Associated Diarrhea

We performed a case-control study to evaluate the association between antibiotic use and Clostridium difficile–associated diarrhea (CDAD), matching for admission unit and time at risk for CDAD. A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confide...

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Detalles Bibliográficos
Autores principales: McCusker, Margaret E., Harris, Anthony D., Perencevich, Eli, Roghmann, Mary-Claire
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2003
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000134/
https://www.ncbi.nlm.nih.gov/pubmed/12781017
http://dx.doi.org/10.3201/eid0906.020385
Descripción
Sumario:We performed a case-control study to evaluate the association between antibiotic use and Clostridium difficile–associated diarrhea (CDAD), matching for admission unit and time at risk for CDAD. A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confidence interval 2.6 to 61.6) was the strongest risk factor for CDAD.

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