The Low-pH Stability Discovered in Neuraminidase of 1918 Pandemic Influenza A Virus Enhances Virus Replication

The “Spanish” pandemic influenza A virus, which killed more than 20 million worldwide in 1918-19, is one of the serious pathogens in recorded history. Characterization of the 1918 pandemic virus reconstructed by reverse genetics showed that PB1, hemagglutinin (HA), and neuraminidase (NA) genes contr...

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Detalles Bibliográficos
Autores principales: Takahashi, Tadanobu, Kurebayashi, Yuuki, Ikeya, Kumiko, Mizuno, Takashi, Fukushima, Keijo, Kawamoto, Hiroko, Kawaoka, Yoshihiro, Suzuki, Yasuo, Suzuki, Takashi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000343/
https://www.ncbi.nlm.nih.gov/pubmed/21151571
http://dx.doi.org/10.1371/journal.pone.0015556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000343/
https://www.ncbi.nlm.nih.gov/pubmed/21151571
http://dx.doi.org/10.1371/journal.pone.0015556

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