Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment

Bacillus anthracis infects hosts as a spore, germinates, and disseminates in its vegetative form. Production of anthrax lethal and edema toxins following bacterial outgrowth results in host death. Macrophages of inbred mouse strains are either sensitive or resistant to lethal toxin depending on whet...

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Detalles Bibliográficos
Autores principales: Moayeri, Mahtab, Crown, Devorah, Newman, Zachary L., Okugawa, Shu, Eckhaus, Michael, Cataisson, Christophe, Liu, Shihui, Sastalla, Inka, Leppla, Stephen H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000361/
https://www.ncbi.nlm.nih.gov/pubmed/21170303
http://dx.doi.org/10.1371/journal.ppat.1001222

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