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Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt

Recent studies have shown that rhesus macaques can perceive visual motion direction in earth-centered coordinates as accurately as humans. We tested whether coordinate frames representing smooth pursuit and/or visual motion signals in medial superior temporal area (MST) are earth centered to better...

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Autores principales: Fujiwara, Keishi, Akao, Teppei, Kurkin, Sergei, Fukushima, Kikuro
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000568/
https://www.ncbi.nlm.nih.gov/pubmed/20421248
http://dx.doi.org/10.1093/cercor/bhq072
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author Fujiwara, Keishi
Akao, Teppei
Kurkin, Sergei
Fukushima, Kikuro
author_facet Fujiwara, Keishi
Akao, Teppei
Kurkin, Sergei
Fukushima, Kikuro
author_sort Fujiwara, Keishi
collection PubMed
description Recent studies have shown that rhesus macaques can perceive visual motion direction in earth-centered coordinates as accurately as humans. We tested whether coordinate frames representing smooth pursuit and/or visual motion signals in medial superior temporal area (MST) are earth centered to better understand its role in coordinating smooth pursuit. In 2 Japanese macaques, we compared preferred directions (re monkeys' head–trunk axis) of pursuit and/or visual motion responses of MSTd neurons while upright and during static whole-body roll-tilt. In the majority (41/51 = 80%) of neurons tested, preferred directions of pursuit and/or visual motion responses were not significantly different while upright and during 40° static roll-tilt. Preferred directions of the remaining 20% of neurons (n = 10) were shifted beyond the range expected from ocular counter-rolling; the maximum shift was 14°, and the mean shift was 12°. These shifts, however, were still less than half of the expected shift if MST signals are coded in the earth-centered coordinates. Virtually, all tested neurons (44/46 = 96%) failed to exhibit a significant difference between resting discharge rate while upright and during static roll-tilt while fixating a stationary spot. These results suggest that smooth pursuit and/or visual motion signals of MST neurons are not coded in the earth-centered coordinates; our results favor the head- and/or trunk-centered coordinates.
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spelling pubmed-30005682010-12-10 Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt Fujiwara, Keishi Akao, Teppei Kurkin, Sergei Fukushima, Kikuro Cereb Cortex Articles Recent studies have shown that rhesus macaques can perceive visual motion direction in earth-centered coordinates as accurately as humans. We tested whether coordinate frames representing smooth pursuit and/or visual motion signals in medial superior temporal area (MST) are earth centered to better understand its role in coordinating smooth pursuit. In 2 Japanese macaques, we compared preferred directions (re monkeys' head–trunk axis) of pursuit and/or visual motion responses of MSTd neurons while upright and during static whole-body roll-tilt. In the majority (41/51 = 80%) of neurons tested, preferred directions of pursuit and/or visual motion responses were not significantly different while upright and during 40° static roll-tilt. Preferred directions of the remaining 20% of neurons (n = 10) were shifted beyond the range expected from ocular counter-rolling; the maximum shift was 14°, and the mean shift was 12°. These shifts, however, were still less than half of the expected shift if MST signals are coded in the earth-centered coordinates. Virtually, all tested neurons (44/46 = 96%) failed to exhibit a significant difference between resting discharge rate while upright and during static roll-tilt while fixating a stationary spot. These results suggest that smooth pursuit and/or visual motion signals of MST neurons are not coded in the earth-centered coordinates; our results favor the head- and/or trunk-centered coordinates. Oxford University Press 2011-01 2010-04-26 /pmc/articles/PMC3000568/ /pubmed/20421248 http://dx.doi.org/10.1093/cercor/bhq072 Text en © The Authors 2010. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Fujiwara, Keishi
Akao, Teppei
Kurkin, Sergei
Fukushima, Kikuro
Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt
title Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt
title_full Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt
title_fullStr Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt
title_full_unstemmed Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt
title_short Activity of Pursuit-Related Neurons in Medial Superior Temporal Area (MST) during Static Roll-Tilt
title_sort activity of pursuit-related neurons in medial superior temporal area (mst) during static roll-tilt
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000568/
https://www.ncbi.nlm.nih.gov/pubmed/20421248
http://dx.doi.org/10.1093/cercor/bhq072
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